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Postdoctoral Research Associate in bioinorganic and organometallic chemistry

£32,817 - £33,797 a year
Yorkshire And The Humber
University of York

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The role holder will work with Prof Anne-Kathrin Duhme-Klair and Prof Keith Wilson in the Department of Chemistry, in collaboration with Dr Steven Johnson in the Department of Electronic Engineering. The project is funded by the EPSRC (UK Engineering and Physical Sciences Research Council) to develop modular and recyclable artificial metalloenzymes that combine the reactivity of synthetic organometallic catalysts with the selectivity and biocompatibility of proteins. The project will apply a catch-and-release approach to artificial enzyme design that provides new opportunities for biocatalysis, in particular access to new-to-nature transformations, component recycling and incorporation into continuous flow processes.

The Department of Chemistry is one of the largest and most successful departments at York and we are renowned internationally for our research. As a department, we strive to provide a working environment that allows all staff and students to contribute fully, to flourish, and to excel. We are proud of our Athena SWAN Gold Award.


You will work with Prof Anne-Kathrin Duhme-Klair and Prof Keith Wilson and their research teams on the development of artificial metalloenzymes that utilise iron-binding siderophores as anchors to connect synthetic organometallic catalysts to protein scaffolds. The project involves organic ligand synthesis, the synthesis of metal complexes, compound purification and characterisation and the investigation and optimisation of catalytic processes. You will play an important role within a multidisciplinary research team that consists of chemists, biochemists, protein chemists, crystallographers and experts in microfluidics.

Where appropriate you will be expected to provide guidance to other researchers within the research groups including project students and PhD students.

You will also be responsible for:

• conducting individual and collaborative research projects

• writing and publicising of high quality manuscripts and delivering presentations at conferences or exhibiting work at other events

• contributing to the preparation of research proposals and applications to external bodies

Skills, Experience & Qualifications needed

The successful candidate should have

  • A PhD in chemistry or equivalent experience
  • A proven track-record and excellent skills in organic ligand synthesis, the synthesis of metal complexes and the ability to perform synthesis under an inert atmosphere
  • Advanced skills in standard purification and characterisation techniques, in particular chromatography
  • Proven ability to record, analyse, manage and interpret complex spectroscopic data
  • Experience and ability in the investigation and optimisation of catalytic processes
  • Highly developed communication skills, both orally and in writing, including publication in journals and delivery of presentations at conferences
  • Ability to plan and prioritise own work in order to meet deadlines, exhibiting self-initiative
  • Highly motivated and professional work ethic, with commitment to high quality research, a collaborative ethos and a willingness to proactively support colleagues and students

The post is full time (with flexibility) and available from 1st January 2020, or as soon as possible thereafter, for up to 36 months

Interview date: 28 November 2019

For informal enquiries: please contact Prof Anne-Kathrin Duhme-Klair (anne.duhme-klair@york.ac.uk)

The Department of Chemistry values all employees for the qualities and skills they bring to the workplace and aims to be a diverse and egalitarian community in which all can thrive

The University is committed to promoting a diverse and inclusive community – a place where we can all be ourselves and succeed on merit. We offer a range of family friendly, inclusive employment policies, flexible working arrangements, staff engagement forums, campus facilities and services to support staff from different backgrounds.

A place where we can ALL be ourselves #EqualityatYork

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